Interstitial Fibrosis in Heart Failure

Interstitial Fibrosis in Heart Failure, edited by Francisco J. Villarreal, M.D., Ph.D., provides a timely and integrative review of the basics of cardiac extracellular matrix structure. Topics covered include how cardiac remodeling influences its disposition, abundance and function; possible non-inv...

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Corporate Author: SpringerLink (Online service)
Other Authors: Villarreal, Francisco J.
Format: Electronic
Language: English
Published: New York, NY : Springer New York, 2005.
Series: Developments in Cardiovascular Medicine, 253
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Table of Contents:
  • Architecture of the Normal and Remodeled Heart
  • The Architecture of the Heart: Myocyte Organization and the Cardiac Extracellular Matrix
  • Extracellular Matrix and Cardiac Remodeling
  • Pro-Inflammatory Cytokines and Cardiac Extracellular Matrix: Regulation of Fibroblast Phenotype
  • Pharmacology of G-Protein-linked Signaling in Cardiac Fibroblasts
  • Diagnostic Tools for the Identification of Myocardial Fibrosis and Changes in Ventricular Mechanics
  • Serum Markers of Fibrillar Collagen Metabolism in Cardiac Diseases
  • Ultrasonic Characterization of the Myocardium
  • The Mechanics of the Fibrosed/Remodeled Heart
  • Pathophysiology of Cardiac Remodeling and Fibrosis
  • Renin Angiotensin Aldosterone System and Cardiac Extracellular Matrix
  • Matrix Metalloproteinases and Myocardial Remodeling
  • Cardiac Mast Cells as Mediators of Ventricular Remodeling
  • Matrix Metalloproteinasses in Cardiac Remodeling
  • Turmoil in the Cardiac Myocyte: Acute Intracellular Activation of Matrix Metalloproteinases
  • Regulation of Cardiac Extracellular Matrix Remodeling Following Myocardial Infarction.
  • Experimental Models of MMP Activation: Ventricular Volume Overload
  • Prospect for Therapy of the Fibrosed Heart
  • Targets for Pharmacological Modulation of Cardiac Fibrosis
  • Biological and Functional Effects of Chronic Mechanical Support Induced by Left Ventricular Assist Devices on Failing Human Myocardium
  • Molecular Strategies for the Prevention of Cardiac Fibrosis
  • Prospects for Gene Therapy for the Fibrosed Heart: Targeting Regulators of Extracellular Matrix Turnover
  • Therapeutic Potential of TIMPs in Heart Failure.